Médiathèque

CARDIOX : Cardiovascular effects of traffic-related air pollution

Inhalation study in rat of NO2 alone or in diesel engine emissions

Description du tableau
Auteur(s) : MONTEIL Christelle, LECUREUR Valérie, MULDER Paul, CAZIER Fabrice
Organisme : UNIVERSITE RENNES, UNIVERSITE ROUEN, ADEME, INSERM, IRSET, ABTE
Collection : Expertise
Description : janvier 2017 - 10 p.
Type de contenu : Etude, Rapport

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Description du tableau
Résumé : The objective of this project was to demonstrate the effects on the cardiovascular system of NO2 alone or as a mixture with other gaseous pollutants emitted by a Euro 4 Diesel engine equipped with a particulate filter. The pollutant emissions, diluted by a factor of 11, were taken upstream and downstream of the particulate filter to assess its impact.

The work was organized around four main tasks:
  1. exposure of animals (Wistar rats) and characterization of Euro 4 diesel engine emissions,
  2. evaluation of cardiac and mitochondrial function,
  3. evaluation of cardiac remodeling
  4. evaluation of the global and genome-wide cellular response.
The results are presented and analyzed by considering single (3 hours) or repeated (3 hours / days and 5 days / week for three weeks) exposures to NO2 or all pollutants.

Détails

Description du tableau
Mots-clés : POLLUTION DE L'AIR, TRANSPORT ROUTIER, NO2, IMPACT SUR LA SANTE, IMPACT SUR ANIMAL, COMPOSE ORGANIQUE, AEROSOL, POLLUANT ATMOSPHERIQUE, PARTICULE ATMOSPHERIQUE, AUTOMOBILE, MOTEUR DIESEL, ZONE URBANISEE
Date de mise en ligne : janvier 2018
Date d'édition : janvier 2017
Langue : EN
Type de support : pdf/A4
Cible(s) concernée(s) : Entreprises et Monde Agricole
Public : Entreprises et fédérations professionnelles, Monde de la recherche